Fig. 1.
(Color online) (a) Schematic diagram of GFET. (b) The Image of the GFET and zoomed-in chip. (c) The fabrication process of the biosensor on graphene surface.
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Banpeng Cao, Changhao Dai, Xuejun Wang, Dacheng Wei. Ultrasensitive detection of methamphetamine by antibody-modified transistor assay[J]. Journal of Semiconductors, 2023, 44(2): 022001. doi: 10.1088/1674-4926/44/2/022001
B P Cao, C H Dai, X J Wang, D C Wei. Ultrasensitive detection of methamphetamine by antibody-modified transistor assay[J]. J. Semicond, 2023, 44(2): 022001. doi: 10.1088/1674-4926/44/2/022001
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Ultrasensitive detection of methamphetamine by antibody-modified transistor assay
doi: 10.1088/1674-4926/44/2/022001
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Abstract
Effective detection of methamphetamine (Met) requires a fast, sensitive, and cheap testing assay. However, commercially available methods require expensive instruments and highly trained operators, which are time-consuming and labor-intensive. Herein, an antibody-modified graphene transistor assay is developed for sensitive and minute-level detection of Met in complex environments. The anti-Met probe captured charged targets within 120 s, leading to a p-doping effect near the graphene channel. The limit of detection reaches 50 aM (5.0 × 10−17 M) Met in solution. The graphene transistor would be a valuable tool for Met detection effective prevention of drug abuse. -
References
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Supplementary materials to this article can be found online at https://doi.org/10.1088/1674-4926/44/2/022001.
§Banpeng Cao and Changhao Dai contributed equally to this work.
§Banpeng Cao and Changhao Dai contributed equally to this work.
