Fig. 1.
(Color online) (a) Schematic diagram of GFET. (b) The Image of the GFET and zoomed-in chip. (c) The fabrication process of the biosensor on graphene surface.
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| Citation: |
Banpeng Cao, Changhao Dai, Xuejun Wang, Dacheng Wei. Ultrasensitive detection of methamphetamine by antibody-modified transistor assay[J]. Journal of Semiconductors, 2023, 44(2): 022001. doi: 10.1088/1674-4926/44/2/022001
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Banpeng Cao, Changhao Dai, Xuejun Wang, Dacheng Wei. 2023: Ultrasensitive detection of methamphetamine by antibody-modified transistor assay. Journal of Semiconductors, 44(2): 022001. doi: 10.1088/1674-4926/44/2/022001
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Ultrasensitive detection of methamphetamine by antibody-modified transistor assay
DOI: 10.1088/1674-4926/44/2/022001
More Information
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Banpeng Cao：received his master degree from Jiangxi Normal University, Jiangxi, China in 2011 and PhD from the Yamaguchi University, Yamaguchi, Japan in 2017. He joined Dacheng Wei's Group at Fudan University as a postdoc researcher in June 2019. His research interests center on preparation of 2D materials and their sensing applications -
Changhao Dai：was born in 1997. He received his bachelor degree from Nanjing University of Science and Technology in 2019. He is currently pursuing a PhD at the Department of Macromolecular Science, Fudan University at Shanghai, China, under the guidance of Prof. Dacheng Wei. His research interests center on preparation of 2D materials and their sensing applications -
Dacheng Wei：is a professor in the Department of Marcomolecular Science, Fudan University, Shanghai, China. He received his B.S. degree from Zhejiang University, Zhejiang, China in 2003 and PhD from the Institute of Chemistry, Chinese Academy of Sciences, Beijing, China in 2009. After his independent research in National University of Singapore, Singapore, he joined Fudan University in 2014. His research interest includes synthesis and electrical applications of 2D materials like graphene, 2D polymers, and so on - Corresponding author: weidc@fudan.edu.cn
- Revised Date: 2022-12-14 Available Online: 2022-12-26
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Abstract
Effective detection of methamphetamine (Met) requires a fast, sensitive, and cheap testing assay. However, commercially available methods require expensive instruments and highly trained operators, which are time-consuming and labor-intensive. Herein, an antibody-modified graphene transistor assay is developed for sensitive and minute-level detection of Met in complex environments. The anti-Met probe captured charged targets within 120 s, leading to a p-doping effect near the graphene channel. The limit of detection reaches 50 aM (5.0 × 10−17 M) Met in solution. The graphene transistor would be a valuable tool for Met detection effective prevention of drug abuse. -
References
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Supplementary materials to this article can be found online at https://doi.org/10.1088/1674-4926/44/2/022001.
§Banpeng Cao and Changhao Dai contributed equally to this work.
§Banpeng Cao and Changhao Dai contributed equally to this work.
